Clipping of news on Brazilian Culture, Law and Citizenship
01/30/2013
This article was translated by an automatic translation system, and was therefore not reviewed by people.
RIO-Scientists now find that women are more sensitive and have more adverse side responses to various drugs, starting with sleeping pills, as recently notified the U.S. health agency, the Food and Drug Administration (FDA). In the case in particular, it was reported that a remedy for insomnia, Intermezzo, is metabolized by men faster than women. The active drug is zolpidem, other drugs used with the same purpose, such as Ambien. Because of the difference in effects, the FDA has halved the recommended dose for females.
The Intermerzzo, as the name suggests, is used for patients who have insomnia in the middle of the night and do not need a drug to take effect for eight hours of sleep, but rather a middle ground. Studies have shown that women may have different reactions with tranquilizers and also with a range of drugs may vary aspirin to anesthesia.
"It's just the tip of the iceberg. There are several differences in responses between men and women for various drugs, some known and some not so. "Said Janie Clayton, director of the Office of Women's Health at the National Institute of Health, USA, to the New York Times.
A report in the American mind that, by 1993, women of childbearing age were excluded from testing new drugs. The restriction, which ended this year, caused a gap in the assessment of the effects of drugs in women. The absence of studies for this population group put in check until the effects of aspirin in women in the indications for coronary heart disease and stroke. A study by the Government Accountability Office, an equivalent to the Court of Audit in the United States, indicated that eight out of 10 drugs withdrawn from the market between 1997 and 2000 offered more health risks for women than men.
And not just because women are smaller than men. They metabolize drugs differently because they have a higher percentage of body fat and spend every month, by fluctuations in hormones, such as the menstrual cycle. Another example is the Seldane, an antihistamine, and drug Propulsid to the gastrointestinal tract, which give more women than men the chance of triggering a fatal cardiac arrhythmia.
But differences can also weigh in favor of women. Some medicines for high blood pressure and antibiotics such as erythromycin, appear to be more effective for females. Moreover, women tend to awaken from anesthesia faster than men, besides they are more sensitive to side effects, according to the Society for the Research of Women's Health, also the USA.
Read more: http://extra.globo.com/noticias/saude-e-ciencia/mulheres-sao-mais-sensiveis-medicamentos-que-homens-7431614.html#ixzz2JT4B3Nrm
Source: Extra Online
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This article was translated by an automatic translation system, and was therefore not reviewed by people.