Clipping of news on Brazilian Culture, Law and Citizenship
01/18/2013
This article was translated by an automatic translation system, and was therefore not reviewed by people.
Treatment in rats acts against the protein plates that form in the brain before and during the development of the disease
Brain normal mouse (left) and with the plaques characteristic of the disease (right)
RIO - An experimental vaccine against Alzheimer's disease is being tested in mice, a treatment based on activation of the immune system against the proteins beta-amyloid plaques that accumulate in the brain and cause neuronal disconnection feature of the disease. The novelty of the study, coordinated by Ramon Cacabelos, Euroespes group, is using proteins involved in liposomes (small pockets of fat) before injecting them into animals.
- This is the breakthrough in the study, because it avoids one of the problems of previous studies, because the idea is not new, in the past decade there were tests including humans, but who died of meningoencephalitis or bleeding - the researcher said the newspaper "El País , "now ensuring that this does not happen, because liposomes attenuate the autoimmune response.
Furthermore, by their composition, the casing formed by lipids similar to those that exist in the coverage of neurons, facilitates transport of the antigen and aid the answer is located.
The results of the study, published in "International Journal of Alzheimer's Disease", the injections have a triple effect. The first is to produce an immune response that eliminates the beta-amyloid plaques in diseased animals, to prevent the formation prone to disease and in healthy animals. Second, there appear cases of meningoencephalitis. And, third, no cases of cerebral haemorrhage.
The product has been patented and is pending approval for human trials. According Cacabelos, the lab would be prepared to make the vaccine in three or four months, even if the requirements for the study of the FDA, the U.S. agency that regulates medicines and foods to request more time. If all goes well, in six or eight years work should be completed.
Source: The Globe - Online
Our news are removed entirely from the sites of our partners. For this reason, we can not change their content even in cases of typos
This article was translated by an automatic translation system, and was therefore not reviewed by people.