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Only 40% of women with breast cancer can preserve, study says

15/10/2012

This article was translated by an automatic translation system, and was therefore not reviewed by people.


 




Store the breast is possible in smaller tumors or good response to treatment
 
The breakthrough in the treatment of breast cancer has allowed the indication increasingly less invasive surgery involving the removal of only a small portion of the breast. Still, the adoption rate of this procedure has been lower than expected. From the point of view of the importance of maintaining the breasts for women's self-esteem, this theme was featured in the Congress of the European Society of Clinical Oncology in Vienna, Austria.

The indication for surgery able to save much of the breast is possible when the tumor is small, or in cases of large tumors, the patient has a good response to neoadjuvant treatment (chemotherapy given before surgery in order to decrease the size of the nodule ).

What the researcher Carmen Criscitiello, European Institute of Oncology, found is that the number of indications for surgery that preserves the breast has not increased in the same proportion that enhance the responses of patients to new therapies neoadjuvant.

To reach this conclusion, it was based on a previous study that evaluated the effectiveness of three strategies of neoadjuvant chemotherapy for 429 patients with HER2 positive tumor type. One group received the drug lapatinib, the other received trastuzumab and a third, the combination of the two therapies. Of the latter group, 51.5% of patients had a complete response to therapy, while the other groups, this rate was 24.7% and 29.5% respectively.

What would be expected that the third group, have responded better, received more nominations from surgeries that preserve the breast. But what happened, according to Carmen Criscitiello, was that in all groups, regardless of treatment response, only 40% of patients were able to save the breast.

-The study highlights a negative attitude that can deprive large fraction of women the chance to preserve their breast, without any medical reason to justify this decision.

She adds that the characteristics of the tumor prior to initial chemotherapy had an important role in deciding the type of surgery.

-One of the goals of neoadjuvant therapy is to achieve a higher rate of breast conservation, but that goal is clearly frustrated that the type of surgery is chosen only according to the initial characteristics of the tumor.

In Brazil

According to Maira Caleffi mastologist, president of Femama (Brazilian Federation of Philanthropic Institutions to Support Breast Health), this process can also be observed in Brazil. For her, despite best conditions to perform surgery that preserves the breast, "what is observed in practice is that many patients are informed by the surgeons who may be best to take it all and still remove the other breast as prophylaxis."

 
Maira points out that this procedure has no scientific backing, unless the woman has a familial genetic mutation that predisposes to cancer.

-This is a disservice that has been done. It is an exaggeration, it does not follow the recommendations of authorities and medical societies.

The decision on what will be the procedure adopted should be shared between doctor and patient, according to the mastologist Wesley Andrade Pereira, Hospital ACCamargo. In cases of large tumors, can both begin treatment with the surgery radical and then introduce the neoadjuvant chemotherapy adopt as to try to save the breast.

-When it preserves the breast, there is a psychological gain. The disadvantage is a higher chance of the tumor returning over ten years.

He notes that the woman who preserves the breast has a better acceptance of their self-image.

For oncological surgeon and gynecologist Fábio Laginha, Hospital July 9, after advances in new drugs against breast cancer, progress is needed in imaging and surgical techniques that allow withdrawal of the exact portion of the breast necessary to eliminate all cancer cells.

-What needs to be done, when choosing this type of neoadjuvant chemotherapy is to make sure the tumor site, mark and monitor its reduction.



Source: R7 News

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This article was translated by an automatic translation system, and was therefore not reviewed by people.

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