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Research discovers how to stimulate the production of liver cells

06/03/2012

This article was translated by an automatic translation system, and was therefore not reviewed by people.

 

 



Scientists at the University of Edinburgh, Scotland, discovered how to increase the production of a regenerative type of cell found in the liver, which may help treat liver diseases such as cirrhosis, according to the latest issue of British 'Nature'.

When the liver is sick, produces many of the bile duct cells, hepatocytes but not sufficient, another class of cells that detoxifies this organ and is responsible for repairing your damaged tissue.

According to a medical staff of the Center for Regenerative Medicine (CMR) of the university, it would be possible to develop a drug that stimulated the creation of hepatocytes instead of cells of the bile duct, which would help in the treatment of diseases such as cirrhosis and chronic hepatitis.

In the study, investigators were able to increase the production of hepatocytes to alter the expression of some genes in liver cells which were advanced over a period of development.

Scientists hope that the long term contribute to accelerate the discovery waiting for liver transplants.

In the UK, liver diseases are the fifth leading cause of death and there are now five hundred patients awaiting transplantation, against three hundred five years ago.

'The liver transplants have saved countless lives over the years, but long-term demand will inevitably exceed the supply of this organ. You must concentrate on the regenerative potential of the human body, "said the head of the CMR, Rob Buckle.

Also participating in the survey the Beatson Institute for Cancer Research in Glasgow, and the Catholic University of Louvain, Belgium.



Source: The Day on Line

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