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Insulin may help in treating Alzheimer“s, says study

This article was translated by an automatic translation system, and was therefore not reviewed by people.




A study done in partnership between the Federal University of Rio de Janeiro and Northwestern University, USA, suggests that insulin can help treat patients with Alzheimer's.

The study, published in the journal Proceedings of the National Academy of Sciences says that insulin can help protect the brain cells that are important for the function of memory.

The relationship between insulin problems and the brain is examined since doctors found evidence of activity of the hormone in the body.

The U.S. and Brazilian research examined the effects of insulin on proteins called ADDLs, which accumulate in patients suffering from Alzheimer's and cause damage to cells.

Scientists took neurons of the hippocampus, a brain with the key role in forming memories.

These neurons were treated with a drug called rosiglitazone, which is administered in people with type 2 diabetes to increase the effect of the hormone in the cells.

After this application, the cells were much less susceptible to damage when exposed to ADDLs protein, suggesting that insulin was able to block the action of the protein.

For the professor William Klein of Northwestern University, medicines that increase the effects of insulin in the brain may open "new avenues" for the treatment of Alzheimer's.

"The sensitivity to insulin may decrease with aging, which presents a new risk factor for Alzheimer's," he said.




Source: O Globo Online

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This article was translated by an automatic translation system, and was therefore not reviewed by people.

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