Clipping of news on Brazilian Culture, Law and Citizenship
07/15/2014
This article was translated by an automatic translation system, and was therefore not reviewed by people.
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The study was done on 10,275 children aged 2 to 14 years who received a total of three doses of vaccine
Mary Leal / File / Brasilia Agency
A study of drug company Sanofi, published on Thursday (10) in the British journal The Lancet, shows that a dengue vaccine has reduced by 88.5% the number of cases of dengue hemorrhagic fever and 56% in the number of cases common disease on tests in three Asian countries. The document also showed 67% decrease in the risk of hospitalizations.
This was the first test of a vaccine against the disease that came to stage 3, applied in a large number of volunteers and last step before the vaccine be submitted to the regulatory bodies of countries. The document, however, does not show the same efficacy above 50% against all four subtypes of common disease. Against subtype 2 lower protection was obtained: 35%. Already in subtypes 3:04 protection reached 75%, and against subtype 1 had 50% efficacy.
The study was done on 10,275 children 2-14 years 12 endemic areas of Malaysia, the Philippines, Thailand and Vietnam. , A total of three doses of vaccine were given.
According to the director of public health at Sanofi, Lucia Bricks, it is common that vaccines have best performance among the most severe forms of the disease, as occurs with the flu.
- The reduction of cases of dengue hemorrhagic fever is of great importance because it reduces the most severe form, which, although rare, is more dangerous.
The vaccine is also being tested in Latin America, including Brazil, with an even larger number of volunteers: 20 000. The result should be published later this year, according to Lucia. After the consolidation of the results of this second phase, the vaccine will be submitted to regulatory agencies in the countries to then be marketed. "We expect this to occur until the end of 2015." The information is the newspaper O Estado de S. Paulo.
Source: R7
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This article was translated by an automatic translation system, and was therefore not reviewed by people.