Clipping of news on Brazilian Culture, Law and Citizenship
02/07/2014
This article was translated by an automatic translation system, and was therefore not reviewed by people.
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Bookmark BRCA 1 on the disease, was also found in women without a family history of cancer Photo: O Globo
RIO - A simple blood test can provide an alert to women if they can get breast cancer even if they have no inheritance of the disease. Researchers have identified a molecule that serves as a "switch" in the blood that increases the chances of women having cancer. To identify the same blood, the chance of having the disease can be identified.
The marker is linked to the breast cancer gene BRCA1 but was also found in women who did not develop the disease, therefore, had no change in this gene.
About 10% of people who have breast cancer have had variations of the BRCA1 and BRCA2 gene inherited from the parents, leaving 90% of the unexplained cases.
A woman with the BRCA1 gene have a 85% risk of developing breast cancer, leading some patients to take the drastic decision to remove the breast as a precaution.
But until now there has been no reliable way to predict the probability of non-hereditary breast cancer.
The change that causes the gene to become cancerous part of the process by which scientists study and show how these genes act. Widschwendter Martin, head of research at University College London, said the discovery opens a new interpretation of the disease.
- Identify an epigenetic signature in women with a BRCA1 mutated gene that was linked to increased risk of cancer and lower survival rates. Surprisingly, we found the same signature in large groups of women without the BRCA1 mutation and, thus, have been able to predict the risk of breast cancer several years before diagnosis. The data are encouraging, since it shows the potential of a blood-based test as a way to identify the risk of breast cancer in women without predisposition.
What proportion of women at risk for breast cancer have epigenetic marker is unknown, but the fact that it is not limited to performing BRCA 1 is significant and the chance to provide this through a blood test, according Widschwendter , is promising.
Read more: http://oglobo.globo.com/sociedade/saude/exame-de-sangue-pode-dar-alerta-sobre-predisposicao-de-cancer-de-mama-13039835#ixzz36K7yGPT9
Source: The Globe - Online
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This article was translated by an automatic translation system, and was therefore not reviewed by people.