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Health

New bird flu can be resistant to drugs in humans, says study

29/05/2013

This article was translated by an automatic translation system, and was therefore not reviewed by people.

 

 

 



H7N9 viruses were resistant to drugs like Tamiflu China.Desde in March, disease has infected at least 130 people and killed 36.Uma team of scientists confirmed first cases of resistance of H7N9 avian influenza viruses to antiviral drugs commonly used against influenza humans, as Tamiflu.Em a study published online on Tuesday (28) in the journal "The Lancet", the Chinese medical Zhenghong Yuang and his team from Fudan University in Shanghai, describe three cases of resistance to antiviral patients infected with H7N9 in the country. Altogether, we analyzed 14 patients with the disease hospitalized in Shanghai Public Health Clinical Centre between 4 and 20 abril.Os patients were treated with the drugs oseltamivir (sold under the trade name Tamiflu) or peramivir. The viral load was investigated in the throat, stool, urine and blood serum of individuals. From these samples, the scientists sequenced the virus's RNA, to study genetic mutations associated with drug resistance and their connection with the evolution of doença.Todos patients evaluated had pneumonia, and seven of them required mechanical ventilation to breathe. Three of these have worsened even more, and two of these died - despite receiving treatment with antiviral medications used corticoides.Os and were related to a reduced charge of avian flu in 11 of 12 patients who sobreviveram.Segundo the authors, the emergence of resistance H7N9 virus is of concern and needs to be closely monitored, with the necessity of planning against possible pandemia.A new bird flu was found on 30 March in patients in eastern China with severe respiratory disease. Since it emerged, the virus has infected at least 130 people and killed 36 in the country. The details involving the appearance and behavior of this micro-organism are not yet fully known.

Source: G1 - News

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