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Researchers test drug that can reverse symptoms of autism

15/03/2013

This article was translated by an automatic translation system, and was therefore not reviewed by people.


 




The scientists found that 17 types of medication corrects abnormalities linked to autism, including social behavior problems

In Rio, priorit Institute seeks to develop children with autism
FABIO ROSSI / THE GLOBE AGENCY

LONDON - A drug that can reverse autism is, for the first time tested in children with the proviso revealed scientists. Preliminary studies showed that the drug, called Suramin, which is already used to treat sleeping sickness in Africa, corrects symptoms similar to autism in rats.

The drug targets a mobile messaging system that produces a metabolic response to stress. According to the new theory, autism is strongly connected to this via known as purinergic signaling. Scientists have discovered that the drug corrects 17 types of abnormalities linked to autism in genetically engineered mice, including problems of social behavior, published the "Daily Mail". 

"Our theory suggests that autism is due to the fact that the cells in a defensive mode emperrarem metabolic and do not communicate with each other smoothly, which may affect the development and function of the brain," said Robert Naviaux, professor of medicine and codirector codirector of the Center for Mitochondrial and Metabolic Diseases, University of California. 

Naviaux recognizes that the correction of anomalies in mice is far from a cure for the human, but it signals that researchers feel encouraged enough for testing this method with children who have autism aspects of next year. 

"This process is in the early stages of development. We believe that this approach, called anti-Purinergic, or APT, offer a new path, fresh and exciting, which could lead to the development of a new class of drugs to treat autism, "he added. 

For Professor Naviaux, the impressive effectiveness of the drug in mice may pave the way for a completely new class of anti-inflammatory drugs to treat autism and other disorders.



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Source: The Globe - Online

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